Defining genetic risk factors for scleroderma-associated interstitial lung disease: IRF5 and STAT4 gene variants are associated with scleroderma while STAT4 is protective against scleroderma-associated interstitial lung disease

Although several genetic associations with scleroderma (SSc) are defined, very little is known on genetic susceptibility to SSc-associated interstitial lung disease (SSc-ILD). A number of common polymorphisms have been associated with SSc-ILD, but most have not been replicated in separate population...

Descripción completa

Detalles Bibliográficos
Autores principales: Stock, Carmel J. W., De Lauretis, Angelo, Visca, Dina, Daccord, Cecile, Kokosi, Maria, Kouranos, Vasilis, Margaritopoulos, George, George, Peter M., Molyneaux, Philip L., Nihtyanova, Svetlana, Chua, Felix, Maher, Toby M., Ong, Voon, Abraham, David J., Denton, Christopher P., Wells, Athol U., Wain, Louise V., Renzoni, Elisabetta A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142048/
https://www.ncbi.nlm.nih.gov/pubmed/31916109
http://dx.doi.org/10.1007/s10067-019-04922-6

Ejemplares similares

Ejemplares similares