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Ospemifene displays broad-spectrum synergistic interactions with itraconazole through potent interference with fungal efflux activities
Azole antifungals are vital therapeutic options for treating invasive mycotic infections. However, the emergence of azole-resistant isolates combined with limited therapeutic options presents a growing challenge in medical mycology. To address this issue, we utilized microdilution checkerboard assay...
Autores principales: | Eldesouky, Hassan E., Salama, Ehab A., Hazbun, Tony R., Mayhoub, Abdelrahman S., Seleem, Mohamed N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142066/ https://www.ncbi.nlm.nih.gov/pubmed/32269301 http://dx.doi.org/10.1038/s41598-020-62976-y |
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