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KIR Variation in Iranians Combines High Haplotype and Allotype Diversity With an Abundance of Functional Inhibitory Receptors

Natural killer (NK) cells are innate lymphocytes that eliminate infected and transformed cells. They discriminate healthy from diseased tissue through killer cell Ig-like receptor (KIR) recognition of HLA class I ligands. Directly impacting NK cell function, KIR polymorphism associates with infectio...

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Detalles Bibliográficos
Autores principales:	Alicata, Claudia, Ashouri, Elham, Nemat-Gorgani, Neda, Guethlein, Lisbeth A., Marin, Wesley M., Tao, Sudan, Moretta, Lorenzo, Hollenbach, Jill A., Trowsdale, John, Traherne, James A., Ghaderi, Abbas, Parham, Peter, Norman, Paul J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142237/ https://www.ncbi.nlm.nih.gov/pubmed/32300348 http://dx.doi.org/10.3389/fimmu.2020.00556

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