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Fanconi Anemia Pathway: Mechanisms of Breast Cancer Predisposition Development and Potential Therapeutic Targets

The maintenance of genomic stability is crucial for species survival, and its failure is closely associated with tumorigenesis. The Fanconi anemia (FA) pathway, involving 22 identified genes, plays a central role in repairing DNA interstrand cross-links. Importantly, a germline defect in any of thes...

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Detalles Bibliográficos
Autores principales:	Fang, Can-Bin, Wu, Hua-Tao, Zhang, Man-Li, Liu, Jing, Zhang, Guo-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142266/ https://www.ncbi.nlm.nih.gov/pubmed/32300589 http://dx.doi.org/10.3389/fcell.2020.00160

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