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Reduced Macrophage Infiltration and Demyelination in Mice Lacking the Chemokine Receptor CCR5 Following Infection with a Neurotropic Coronavirus

Studies were performed to investigate the contributions of the CC chemokine receptor CCR5 in host defense and disease development following intracranial infection with mouse hepatitis virus (MHV). T cell recruitment was impaired in MHV-infected CCR5(−/−) mice at day 7 postinfection (pi), which corre...

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Detalles Bibliográficos
Autores principales: Glass, William G., Liu, Michael T., Kuziel, William A., Lane, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press. 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142305/
https://www.ncbi.nlm.nih.gov/pubmed/11543653
http://dx.doi.org/10.1006/viro.2001.1050