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Reduced Macrophage Infiltration and Demyelination in Mice Lacking the Chemokine Receptor CCR5 Following Infection with a Neurotropic Coronavirus
Studies were performed to investigate the contributions of the CC chemokine receptor CCR5 in host defense and disease development following intracranial infection with mouse hepatitis virus (MHV). T cell recruitment was impaired in MHV-infected CCR5(−/−) mice at day 7 postinfection (pi), which corre...
Autores principales: | Glass, William G., Liu, Michael T., Kuziel, William A., Lane, Thomas E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press.
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142305/ https://www.ncbi.nlm.nih.gov/pubmed/11543653 http://dx.doi.org/10.1006/viro.2001.1050 |
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