The DNMT1/miR-34a/FOXM1 Axis Contributes to Stemness of Liver Cancer Cells

BACKGROUND: Whether DNA methyltransferase 1 (DNMT1)/miR-34a/FoxM1 signaling promotes the stemness of liver cancer stem cells (LCSCs) remains unclear. This study aimed to assess whether methylation-based silencing of miR-34a by DNMT1 contributes to stemness features via FoxM1 upregulation in LCSCs. M...

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Detalles Bibliográficos
Autores principales: Cao, Xiaocheng, Liu, Lihua, Cao, Xiaozheng, Cui, Yinghong, Zou, Chang, Chen, A., Qiu, Yebei, Quan, Meifang, Ren, Kaiqun, Chen, Xiangding, Cao, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142390/
https://www.ncbi.nlm.nih.gov/pubmed/32308683
http://dx.doi.org/10.1155/2020/8978930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142390/
https://www.ncbi.nlm.nih.gov/pubmed/32308683
http://dx.doi.org/10.1155/2020/8978930

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