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Microfluidic In-Situ Measurement of Poisson’s Ratio of Hydrogels

Being able to precisely characterize the mechanical properties of soft microparticles is essential for numerous situations, from the understanding of the flow of biological fluids to the development of soft micro-robots. Here, we present a simple measurement technique for determining Poisson’s ratio...

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Autores principales: Cappello, Jean, d’Herbemont, Vincent, Lindner, Anke, du Roure, Olivia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142615/
https://www.ncbi.nlm.nih.gov/pubmed/32204340
http://dx.doi.org/10.3390/mi11030318
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author Cappello, Jean
d’Herbemont, Vincent
Lindner, Anke
du Roure, Olivia
author_facet Cappello, Jean
d’Herbemont, Vincent
Lindner, Anke
du Roure, Olivia
author_sort Cappello, Jean
collection PubMed
description Being able to precisely characterize the mechanical properties of soft microparticles is essential for numerous situations, from the understanding of the flow of biological fluids to the development of soft micro-robots. Here, we present a simple measurement technique for determining Poisson’s ratio of soft micron-sized hydrogels in the presence of a surrounding liquid. This method relies on the measurement of the deformation, in two orthogonal directions, of a rectangular hydrogel slab compressed uni-axially inside a microfluidic channel. Due to the in situ character of the method, the sample does not need to be dried, allowing for the measurement of the mechanical properties of swollen hydrogels. Using this method, we determined Poisson’s ratio of hydrogel particles composed of polyethylene glycol (PEG) and varying solvents fabricated using a lithography technique. The results demonstrate, with high precision, the dependence of the hydrogel compressibility on the solvent fraction and character. The method is easy to implement and can be adapted for the measurement of a variety of soft and biological materials.
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spelling pubmed-71426152020-04-15 Microfluidic In-Situ Measurement of Poisson’s Ratio of Hydrogels Cappello, Jean d’Herbemont, Vincent Lindner, Anke du Roure, Olivia Micromachines (Basel) Article Being able to precisely characterize the mechanical properties of soft microparticles is essential for numerous situations, from the understanding of the flow of biological fluids to the development of soft micro-robots. Here, we present a simple measurement technique for determining Poisson’s ratio of soft micron-sized hydrogels in the presence of a surrounding liquid. This method relies on the measurement of the deformation, in two orthogonal directions, of a rectangular hydrogel slab compressed uni-axially inside a microfluidic channel. Due to the in situ character of the method, the sample does not need to be dried, allowing for the measurement of the mechanical properties of swollen hydrogels. Using this method, we determined Poisson’s ratio of hydrogel particles composed of polyethylene glycol (PEG) and varying solvents fabricated using a lithography technique. The results demonstrate, with high precision, the dependence of the hydrogel compressibility on the solvent fraction and character. The method is easy to implement and can be adapted for the measurement of a variety of soft and biological materials. MDPI 2020-03-19 /pmc/articles/PMC7142615/ /pubmed/32204340 http://dx.doi.org/10.3390/mi11030318 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Cappello, Jean
d’Herbemont, Vincent
Lindner, Anke
du Roure, Olivia
Microfluidic In-Situ Measurement of Poisson’s Ratio of Hydrogels
title Microfluidic In-Situ Measurement of Poisson’s Ratio of Hydrogels
title_full Microfluidic In-Situ Measurement of Poisson’s Ratio of Hydrogels
title_fullStr Microfluidic In-Situ Measurement of Poisson’s Ratio of Hydrogels
title_full_unstemmed Microfluidic In-Situ Measurement of Poisson’s Ratio of Hydrogels
title_short Microfluidic In-Situ Measurement of Poisson’s Ratio of Hydrogels
title_sort microfluidic in-situ measurement of poisson’s ratio of hydrogels
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142615/
https://www.ncbi.nlm.nih.gov/pubmed/32204340
http://dx.doi.org/10.3390/mi11030318
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