Downregulation of SNRPG induces cell cycle arrest and sensitizes human glioblastoma cells to temozolomide by targeting Myc through a p53-dependent signaling pathway

Objective: Temozolomide (TMZ) is commonly used for glioblastoma multiforme (GBM) chemotherapy. However, drug resistance limits its therapeutic effect in GBM treatment. RNA-binding proteins (RBPs) have vital roles in posttranscriptional events. While disturbance of RBP-RNA network activity is potenti...

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Detalles Bibliográficos
Autores principales: Lan, Yulong, Lou, Jiacheng, Hu, Jiliang, Yu, Zhikuan, Lyu, Wen, Zhang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142844/
https://www.ncbi.nlm.nih.gov/pubmed/32296580
http://dx.doi.org/10.20892/j.issn.2095-3941.2019.0164

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