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Microparticle Acoustophoresis in Aluminum-Based Acoustofluidic Devices with PDMS Covers

We present a numerical model for the recently introduced simple and inexpensive micromachined aluminum devices with a polydimethylsiloxane (PDMS) cover for microparticle acoustophoresis. We validate the model experimentally for a basic design, where a microchannel is milled into the surface of an al...

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Detalles Bibliográficos
Autores principales: Bodé, William Naundrup, Jiang, Lei, Laurell, Thomas, Bruus, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7143328/
https://www.ncbi.nlm.nih.gov/pubmed/32168805
http://dx.doi.org/10.3390/mi11030292
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author Bodé, William Naundrup
Jiang, Lei
Laurell, Thomas
Bruus, Henrik
author_facet Bodé, William Naundrup
Jiang, Lei
Laurell, Thomas
Bruus, Henrik
author_sort Bodé, William Naundrup
collection PubMed
description We present a numerical model for the recently introduced simple and inexpensive micromachined aluminum devices with a polydimethylsiloxane (PDMS) cover for microparticle acoustophoresis. We validate the model experimentally for a basic design, where a microchannel is milled into the surface of an aluminum substrate, sealed with a PDMS cover, and driven at MHz frequencies by a piezoelectric lead-zirconate-titanate (PZT) transducer. Both experimentally and numerically we find that the soft PDMS cover suppresses the Rayleigh streaming rolls in the bulk. However, due to the low transverse speed of sound in PDMS, such devices are prone to exhibit acoustic streaming vortices in the corners with a relatively large velocity. We predict numerically that in devices, where the microchannel is milled all the way through the aluminum substrate and sealed with a PDMS cover on both the top and bottom, the Rayleigh streaming is suppressed in the bulk thus enabling focusing of sub-micrometer-sized particles.
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spelling pubmed-71433282020-04-14 Microparticle Acoustophoresis in Aluminum-Based Acoustofluidic Devices with PDMS Covers Bodé, William Naundrup Jiang, Lei Laurell, Thomas Bruus, Henrik Micromachines (Basel) Article We present a numerical model for the recently introduced simple and inexpensive micromachined aluminum devices with a polydimethylsiloxane (PDMS) cover for microparticle acoustophoresis. We validate the model experimentally for a basic design, where a microchannel is milled into the surface of an aluminum substrate, sealed with a PDMS cover, and driven at MHz frequencies by a piezoelectric lead-zirconate-titanate (PZT) transducer. Both experimentally and numerically we find that the soft PDMS cover suppresses the Rayleigh streaming rolls in the bulk. However, due to the low transverse speed of sound in PDMS, such devices are prone to exhibit acoustic streaming vortices in the corners with a relatively large velocity. We predict numerically that in devices, where the microchannel is milled all the way through the aluminum substrate and sealed with a PDMS cover on both the top and bottom, the Rayleigh streaming is suppressed in the bulk thus enabling focusing of sub-micrometer-sized particles. MDPI 2020-03-11 /pmc/articles/PMC7143328/ /pubmed/32168805 http://dx.doi.org/10.3390/mi11030292 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bodé, William Naundrup
Jiang, Lei
Laurell, Thomas
Bruus, Henrik
Microparticle Acoustophoresis in Aluminum-Based Acoustofluidic Devices with PDMS Covers
title Microparticle Acoustophoresis in Aluminum-Based Acoustofluidic Devices with PDMS Covers
title_full Microparticle Acoustophoresis in Aluminum-Based Acoustofluidic Devices with PDMS Covers
title_fullStr Microparticle Acoustophoresis in Aluminum-Based Acoustofluidic Devices with PDMS Covers
title_full_unstemmed Microparticle Acoustophoresis in Aluminum-Based Acoustofluidic Devices with PDMS Covers
title_short Microparticle Acoustophoresis in Aluminum-Based Acoustofluidic Devices with PDMS Covers
title_sort microparticle acoustophoresis in aluminum-based acoustofluidic devices with pdms covers
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7143328/
https://www.ncbi.nlm.nih.gov/pubmed/32168805
http://dx.doi.org/10.3390/mi11030292
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