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Increased Risk of Sensorineural Hearing Loss as a Result of Exposure to Air Pollution

Whether exposure to air pollution is associated with developing sensorineural hearing loss (SHL) remains controversial. Using data from the National Health Insurance Research Database, we recruited a total of 75,767 subjects aged older than 20 years with no history of SHL from 1998 to 2010, and they...

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Autores principales: Chang, Kuang-Hsi, Tsai, Stella Chin-Shaw, Lee, Chang-Yin, Chou, Ruey-Hwang, Fan, Hueng-Chuen, Lin, Frank Cheau-Feng, Lin, Cheng-Li, Hsu, Yi-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7143358/
https://www.ncbi.nlm.nih.gov/pubmed/32192124
http://dx.doi.org/10.3390/ijerph17061969
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author Chang, Kuang-Hsi
Tsai, Stella Chin-Shaw
Lee, Chang-Yin
Chou, Ruey-Hwang
Fan, Hueng-Chuen
Lin, Frank Cheau-Feng
Lin, Cheng-Li
Hsu, Yi-Chao
author_facet Chang, Kuang-Hsi
Tsai, Stella Chin-Shaw
Lee, Chang-Yin
Chou, Ruey-Hwang
Fan, Hueng-Chuen
Lin, Frank Cheau-Feng
Lin, Cheng-Li
Hsu, Yi-Chao
author_sort Chang, Kuang-Hsi
collection PubMed
description Whether exposure to air pollution is associated with developing sensorineural hearing loss (SHL) remains controversial. Using data from the National Health Insurance Research Database, we recruited a total of 75,767 subjects aged older than 20 years with no history of SHL from 1998 to 2010, and they were followed up until SHL was observed, they withdrew from the National Health Insurance program, or the study ended. The subjects were evenly exposed to low-level, mid-level, and high-level carbon monoxide (CO) and nitrogen dioxide (NO(2)). The incidence rate ratio of SHL for patients exposed to high-level CO was 1.24 (95% confidence interval (CI) = 1.14–1.36). The NO(2) pollutants increased the incidence rate ratios of SHL in mid-level NO(2) and high-level NO(2) exposures by 1.10 (95% CI = 1.10–1.32) and 1.36 (95% CI = 1.24–1.49) times, respectively. The adjusted hazard ratio (adj. HR) of SHL in patients exposed to high-level CO was 1.45 (95% CI = 1.31–1.59), relative to that of patients exposed to low-level CO. Compared to patients exposed to low-level NO(2), patients exposed to mid-level NO(2) (adj. HR = 1.40, 95% CI = 1.27–1.54) and high-level NO(2) (adj. HR = 1.63, 95% CI = 1.48–1.81) had a higher risk of developing SHL. The increased risk of SHL following the increased concentrations of air pollutants (CO and NO(2)) was statistically significant in this study. In conclusion, the subjects’ exposure to air pollution exhibited a significantly higher risk of developing SHL in Taiwan.
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spelling pubmed-71433582020-04-14 Increased Risk of Sensorineural Hearing Loss as a Result of Exposure to Air Pollution Chang, Kuang-Hsi Tsai, Stella Chin-Shaw Lee, Chang-Yin Chou, Ruey-Hwang Fan, Hueng-Chuen Lin, Frank Cheau-Feng Lin, Cheng-Li Hsu, Yi-Chao Int J Environ Res Public Health Article Whether exposure to air pollution is associated with developing sensorineural hearing loss (SHL) remains controversial. Using data from the National Health Insurance Research Database, we recruited a total of 75,767 subjects aged older than 20 years with no history of SHL from 1998 to 2010, and they were followed up until SHL was observed, they withdrew from the National Health Insurance program, or the study ended. The subjects were evenly exposed to low-level, mid-level, and high-level carbon monoxide (CO) and nitrogen dioxide (NO(2)). The incidence rate ratio of SHL for patients exposed to high-level CO was 1.24 (95% confidence interval (CI) = 1.14–1.36). The NO(2) pollutants increased the incidence rate ratios of SHL in mid-level NO(2) and high-level NO(2) exposures by 1.10 (95% CI = 1.10–1.32) and 1.36 (95% CI = 1.24–1.49) times, respectively. The adjusted hazard ratio (adj. HR) of SHL in patients exposed to high-level CO was 1.45 (95% CI = 1.31–1.59), relative to that of patients exposed to low-level CO. Compared to patients exposed to low-level NO(2), patients exposed to mid-level NO(2) (adj. HR = 1.40, 95% CI = 1.27–1.54) and high-level NO(2) (adj. HR = 1.63, 95% CI = 1.48–1.81) had a higher risk of developing SHL. The increased risk of SHL following the increased concentrations of air pollutants (CO and NO(2)) was statistically significant in this study. In conclusion, the subjects’ exposure to air pollution exhibited a significantly higher risk of developing SHL in Taiwan. MDPI 2020-03-17 2020-03 /pmc/articles/PMC7143358/ /pubmed/32192124 http://dx.doi.org/10.3390/ijerph17061969 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chang, Kuang-Hsi
Tsai, Stella Chin-Shaw
Lee, Chang-Yin
Chou, Ruey-Hwang
Fan, Hueng-Chuen
Lin, Frank Cheau-Feng
Lin, Cheng-Li
Hsu, Yi-Chao
Increased Risk of Sensorineural Hearing Loss as a Result of Exposure to Air Pollution
title Increased Risk of Sensorineural Hearing Loss as a Result of Exposure to Air Pollution
title_full Increased Risk of Sensorineural Hearing Loss as a Result of Exposure to Air Pollution
title_fullStr Increased Risk of Sensorineural Hearing Loss as a Result of Exposure to Air Pollution
title_full_unstemmed Increased Risk of Sensorineural Hearing Loss as a Result of Exposure to Air Pollution
title_short Increased Risk of Sensorineural Hearing Loss as a Result of Exposure to Air Pollution
title_sort increased risk of sensorineural hearing loss as a result of exposure to air pollution
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7143358/
https://www.ncbi.nlm.nih.gov/pubmed/32192124
http://dx.doi.org/10.3390/ijerph17061969
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