Cargando…

Evaluation of Prevalence of the Sarcopenia Level Using Machine Learning Techniques: Case Study in Tijuana Baja California, Mexico

The article presents a study based on timeline data analysis of the level of sarcopenia in older patients in Baja California, Mexico. Information was examined at the beginning of the study (first event), three months later (second event), and six months later (third event). Sarcopenia is defined as...

Descripción completa

Detalles Bibliográficos
Autores principales: Castillo-Olea, Cristián, Garcia-Zapirain Soto, Begonya, Zuñiga, Clemente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7143671/
https://www.ncbi.nlm.nih.gov/pubmed/32183494
http://dx.doi.org/10.3390/ijerph17061917
_version_ 1783519667124436992
author Castillo-Olea, Cristián
Garcia-Zapirain Soto, Begonya
Zuñiga, Clemente
author_facet Castillo-Olea, Cristián
Garcia-Zapirain Soto, Begonya
Zuñiga, Clemente
author_sort Castillo-Olea, Cristián
collection PubMed
description The article presents a study based on timeline data analysis of the level of sarcopenia in older patients in Baja California, Mexico. Information was examined at the beginning of the study (first event), three months later (second event), and six months later (third event). Sarcopenia is defined as the loss of muscle mass quality and strength. The study was conducted with 166 patients. A total of 65% were women and 35% were men. The mean age of the enrolled patients was 77.24 years. The research included 99 variables that consider medical history, pharmacology, psychological tests, comorbidity (Charlson), functional capacity (Barthel and Lawton), undernourishment (mini nutritional assessment (MNA) validated test), as well as biochemical and socio-demographic data. Our aim was to evaluate the prevalence of the level of sarcopenia in a population of chronically ill patients assessed at the Tijuana General Hospital. We used machine learning techniques to assess and identify the determining variables to focus on the patients’ evolution. The following classifiers were used: Support Vector Machines, Linear Support Vector Machines, Radial Basis Function, Gaussian process, Decision Tree, Random Forest, multilayer perceptron, AdaBoost, Gaussian Naive Bayes, and Quadratic Discriminant Analysis. In order of importance, we found that the following variables determine the level of sarcopenia: Age, Systolic arterial hypertension, mini nutritional assessment (MNA), Number of chronic diseases, and Sodium. They are therefore considered relevant in the decision-making process of choosing treatment or prevention. Analysis of the relationship between the presence of the variables and the classifiers used to measure sarcopenia revealed that the Decision Tree classifier, with the Age, Systolic arterial hypertension, MNA, Number of chronic diseases, and Sodium variables, showed a precision of 0.864, accuracy of 0.831, and an F1 score of 0.900 in the first and second events. Precision of 0.867, accuracy of 0.825, and an F1 score of 0.867 were obtained in event three with the same variables. We can therefore conclude that the Decision Tree classifier yields the best results for the assessment of the determining variables and suggests that the study population’s sarcopenia did not change from moderate to severe.
format Online
Article
Text
id pubmed-7143671
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-71436712020-04-14 Evaluation of Prevalence of the Sarcopenia Level Using Machine Learning Techniques: Case Study in Tijuana Baja California, Mexico Castillo-Olea, Cristián Garcia-Zapirain Soto, Begonya Zuñiga, Clemente Int J Environ Res Public Health Article The article presents a study based on timeline data analysis of the level of sarcopenia in older patients in Baja California, Mexico. Information was examined at the beginning of the study (first event), three months later (second event), and six months later (third event). Sarcopenia is defined as the loss of muscle mass quality and strength. The study was conducted with 166 patients. A total of 65% were women and 35% were men. The mean age of the enrolled patients was 77.24 years. The research included 99 variables that consider medical history, pharmacology, psychological tests, comorbidity (Charlson), functional capacity (Barthel and Lawton), undernourishment (mini nutritional assessment (MNA) validated test), as well as biochemical and socio-demographic data. Our aim was to evaluate the prevalence of the level of sarcopenia in a population of chronically ill patients assessed at the Tijuana General Hospital. We used machine learning techniques to assess and identify the determining variables to focus on the patients’ evolution. The following classifiers were used: Support Vector Machines, Linear Support Vector Machines, Radial Basis Function, Gaussian process, Decision Tree, Random Forest, multilayer perceptron, AdaBoost, Gaussian Naive Bayes, and Quadratic Discriminant Analysis. In order of importance, we found that the following variables determine the level of sarcopenia: Age, Systolic arterial hypertension, mini nutritional assessment (MNA), Number of chronic diseases, and Sodium. They are therefore considered relevant in the decision-making process of choosing treatment or prevention. Analysis of the relationship between the presence of the variables and the classifiers used to measure sarcopenia revealed that the Decision Tree classifier, with the Age, Systolic arterial hypertension, MNA, Number of chronic diseases, and Sodium variables, showed a precision of 0.864, accuracy of 0.831, and an F1 score of 0.900 in the first and second events. Precision of 0.867, accuracy of 0.825, and an F1 score of 0.867 were obtained in event three with the same variables. We can therefore conclude that the Decision Tree classifier yields the best results for the assessment of the determining variables and suggests that the study population’s sarcopenia did not change from moderate to severe. MDPI 2020-03-15 2020-03 /pmc/articles/PMC7143671/ /pubmed/32183494 http://dx.doi.org/10.3390/ijerph17061917 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Castillo-Olea, Cristián
Garcia-Zapirain Soto, Begonya
Zuñiga, Clemente
Evaluation of Prevalence of the Sarcopenia Level Using Machine Learning Techniques: Case Study in Tijuana Baja California, Mexico
title Evaluation of Prevalence of the Sarcopenia Level Using Machine Learning Techniques: Case Study in Tijuana Baja California, Mexico
title_full Evaluation of Prevalence of the Sarcopenia Level Using Machine Learning Techniques: Case Study in Tijuana Baja California, Mexico
title_fullStr Evaluation of Prevalence of the Sarcopenia Level Using Machine Learning Techniques: Case Study in Tijuana Baja California, Mexico
title_full_unstemmed Evaluation of Prevalence of the Sarcopenia Level Using Machine Learning Techniques: Case Study in Tijuana Baja California, Mexico
title_short Evaluation of Prevalence of the Sarcopenia Level Using Machine Learning Techniques: Case Study in Tijuana Baja California, Mexico
title_sort evaluation of prevalence of the sarcopenia level using machine learning techniques: case study in tijuana baja california, mexico
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7143671/
https://www.ncbi.nlm.nih.gov/pubmed/32183494
http://dx.doi.org/10.3390/ijerph17061917
work_keys_str_mv AT castillooleacristian evaluationofprevalenceofthesarcopenialevelusingmachinelearningtechniquescasestudyintijuanabajacaliforniamexico
AT garciazapirainsotobegonya evaluationofprevalenceofthesarcopenialevelusingmachinelearningtechniquescasestudyintijuanabajacaliforniamexico
AT zunigaclemente evaluationofprevalenceofthesarcopenialevelusingmachinelearningtechniquescasestudyintijuanabajacaliforniamexico