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Advanced Technologies for the Extraction of Marine Brown Algal Polysaccharides

Over the years, brown algae bioactive polysaccharides laminarin, alginate and fucoidan have been isolated and used in functional foods, cosmeceutical and pharmaceutical industries. The extraction process of these polysaccharides includes several complex and time-consuming steps and the correct adjus...

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Autores principales: Dobrinčić, Ana, Balbino, Sandra, Zorić, Zoran, Pedisić, Sandra, Bursać Kovačević, Danijela, Elez Garofulić, Ivona, Dragović-Uzelac, Verica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7143672/
https://www.ncbi.nlm.nih.gov/pubmed/32197494
http://dx.doi.org/10.3390/md18030168
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author Dobrinčić, Ana
Balbino, Sandra
Zorić, Zoran
Pedisić, Sandra
Bursać Kovačević, Danijela
Elez Garofulić, Ivona
Dragović-Uzelac, Verica
author_facet Dobrinčić, Ana
Balbino, Sandra
Zorić, Zoran
Pedisić, Sandra
Bursać Kovačević, Danijela
Elez Garofulić, Ivona
Dragović-Uzelac, Verica
author_sort Dobrinčić, Ana
collection PubMed
description Over the years, brown algae bioactive polysaccharides laminarin, alginate and fucoidan have been isolated and used in functional foods, cosmeceutical and pharmaceutical industries. The extraction process of these polysaccharides includes several complex and time-consuming steps and the correct adjustment of extraction parameters (e.g., time, temperature, power, pressure, solvent and sample to solvent ratio) greatly influences the yield, physical, chemical and biochemical properties as well as their biological activities. This review includes the most recent conventional procedures for brown algae polysaccharides extraction along with advanced extraction techniques (microwave-assisted extraction, ultrasound assisted extraction, pressurized liquid extraction and enzymes assisted extraction) which can effectively improve extraction process. The influence of these extraction techniques and their individual parameters on yield, chemical structure and biological activities from the most current literature is discussed, along with their potential for commercial applications as bioactive compounds and drug delivery systems.
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spelling pubmed-71436722020-04-14 Advanced Technologies for the Extraction of Marine Brown Algal Polysaccharides Dobrinčić, Ana Balbino, Sandra Zorić, Zoran Pedisić, Sandra Bursać Kovačević, Danijela Elez Garofulić, Ivona Dragović-Uzelac, Verica Mar Drugs Review Over the years, brown algae bioactive polysaccharides laminarin, alginate and fucoidan have been isolated and used in functional foods, cosmeceutical and pharmaceutical industries. The extraction process of these polysaccharides includes several complex and time-consuming steps and the correct adjustment of extraction parameters (e.g., time, temperature, power, pressure, solvent and sample to solvent ratio) greatly influences the yield, physical, chemical and biochemical properties as well as their biological activities. This review includes the most recent conventional procedures for brown algae polysaccharides extraction along with advanced extraction techniques (microwave-assisted extraction, ultrasound assisted extraction, pressurized liquid extraction and enzymes assisted extraction) which can effectively improve extraction process. The influence of these extraction techniques and their individual parameters on yield, chemical structure and biological activities from the most current literature is discussed, along with their potential for commercial applications as bioactive compounds and drug delivery systems. MDPI 2020-03-18 /pmc/articles/PMC7143672/ /pubmed/32197494 http://dx.doi.org/10.3390/md18030168 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Dobrinčić, Ana
Balbino, Sandra
Zorić, Zoran
Pedisić, Sandra
Bursać Kovačević, Danijela
Elez Garofulić, Ivona
Dragović-Uzelac, Verica
Advanced Technologies for the Extraction of Marine Brown Algal Polysaccharides
title Advanced Technologies for the Extraction of Marine Brown Algal Polysaccharides
title_full Advanced Technologies for the Extraction of Marine Brown Algal Polysaccharides
title_fullStr Advanced Technologies for the Extraction of Marine Brown Algal Polysaccharides
title_full_unstemmed Advanced Technologies for the Extraction of Marine Brown Algal Polysaccharides
title_short Advanced Technologies for the Extraction of Marine Brown Algal Polysaccharides
title_sort advanced technologies for the extraction of marine brown algal polysaccharides
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7143672/
https://www.ncbi.nlm.nih.gov/pubmed/32197494
http://dx.doi.org/10.3390/md18030168
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