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Recent Developments of Flexible and Stretchable Electrochemical Biosensors

The skyrocketing popularity of health monitoring has spurred increasing interest in wearable electrochemical biosensors. Compared with the traditionally rigid and bulky electrochemical biosensors, flexible and stretchable devices render a unique capability to conform to the complex, hierarchically t...

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Detalles Bibliográficos
Autores principales: Yang, Xudong, Cheng, Huanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7143805/
https://www.ncbi.nlm.nih.gov/pubmed/32111023
http://dx.doi.org/10.3390/mi11030243
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author Yang, Xudong
Cheng, Huanyu
author_facet Yang, Xudong
Cheng, Huanyu
author_sort Yang, Xudong
collection PubMed
description The skyrocketing popularity of health monitoring has spurred increasing interest in wearable electrochemical biosensors. Compared with the traditionally rigid and bulky electrochemical biosensors, flexible and stretchable devices render a unique capability to conform to the complex, hierarchically textured surfaces of the human body. With a recognition element (e.g., enzymes, antibodies, nucleic acids, ions) to selectively react with the target analyte, wearable electrochemical biosensors can convert the types and concentrations of chemical changes in the body into electrical signals for easy readout. Initial exploration of wearable electrochemical biosensors integrates electrodes on textile and flexible thin-film substrate materials. A stretchable property is needed for the thin-film device to form an intimate contact with the textured skin surface and to deform with various natural skin motions. Thus, stretchable materials and structures have been exploited to ensure the effective function of a wearable electrochemical biosensor. In this mini-review, we summarize the recent development of flexible and stretchable electrochemical biosensors, including their principles, representative application scenarios (e.g., saliva, tear, sweat, and interstitial fluid), and materials and structures. While great strides have been made in the wearable electrochemical biosensors, challenges still exist, which represents a small fraction of opportunities for the future development of this burgeoning field.
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spelling pubmed-71438052020-04-14 Recent Developments of Flexible and Stretchable Electrochemical Biosensors Yang, Xudong Cheng, Huanyu Micromachines (Basel) Review The skyrocketing popularity of health monitoring has spurred increasing interest in wearable electrochemical biosensors. Compared with the traditionally rigid and bulky electrochemical biosensors, flexible and stretchable devices render a unique capability to conform to the complex, hierarchically textured surfaces of the human body. With a recognition element (e.g., enzymes, antibodies, nucleic acids, ions) to selectively react with the target analyte, wearable electrochemical biosensors can convert the types and concentrations of chemical changes in the body into electrical signals for easy readout. Initial exploration of wearable electrochemical biosensors integrates electrodes on textile and flexible thin-film substrate materials. A stretchable property is needed for the thin-film device to form an intimate contact with the textured skin surface and to deform with various natural skin motions. Thus, stretchable materials and structures have been exploited to ensure the effective function of a wearable electrochemical biosensor. In this mini-review, we summarize the recent development of flexible and stretchable electrochemical biosensors, including their principles, representative application scenarios (e.g., saliva, tear, sweat, and interstitial fluid), and materials and structures. While great strides have been made in the wearable electrochemical biosensors, challenges still exist, which represents a small fraction of opportunities for the future development of this burgeoning field. MDPI 2020-02-26 /pmc/articles/PMC7143805/ /pubmed/32111023 http://dx.doi.org/10.3390/mi11030243 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Yang, Xudong
Cheng, Huanyu
Recent Developments of Flexible and Stretchable Electrochemical Biosensors
title Recent Developments of Flexible and Stretchable Electrochemical Biosensors
title_full Recent Developments of Flexible and Stretchable Electrochemical Biosensors
title_fullStr Recent Developments of Flexible and Stretchable Electrochemical Biosensors
title_full_unstemmed Recent Developments of Flexible and Stretchable Electrochemical Biosensors
title_short Recent Developments of Flexible and Stretchable Electrochemical Biosensors
title_sort recent developments of flexible and stretchable electrochemical biosensors
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7143805/
https://www.ncbi.nlm.nih.gov/pubmed/32111023
http://dx.doi.org/10.3390/mi11030243
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