Unmethylated CpG motif-containing genomic DNA fragment of Bacillus calmette-guerin promotes macrophage functions through TLR9-mediated activation of NF-κB and MAPKs signaling pathways

The potency of synthetic CpG-oligo-deoxynucleotides (CpG-ODNs) adjuvants in modulating the immune cell functions through the TLR pathway has been tested and reported previously. However, the cellular signaling involved in the stimulation of macrophages by natural, CpG motif-containing adjuvant and t...

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Detalles Bibliográficos
Autores principales: Li, Junli, Fu, Lili, Wang, Guozhi, Subbian, Selvakumar, Qin, Chuan, Zhao, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144034/
https://www.ncbi.nlm.nih.gov/pubmed/31615313
http://dx.doi.org/10.1177/1753425919879997

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