Citrate stabilized Fe(3)O(4)/DMG modified carbon paste electrode for determination of octamethylcyclotetrasiloxane in blood plasma and urine samples of cement factory workers

In this paper, a novel mercury-free electrochemical probe was constructed for the trace determination of octamethylcyclotetrasiloxane (D(4)) in some biological fluids by adsorptive stripping voltammetry. The platform is based on the adsorptive accumulation of Ni(II) onto a carbon paste electrode modified with citrate stabilized Fe(3)O(4) (Cit-Fe(3)O(4)) and dimethylglyoxime (DMG). It was shown that trace levels of D(4) enhance the electrochemical adsorptive stripping signal of Ni(II) on the electrode platform. It was shown that electrochemical signals are proportional to concentrations of D(4). The supporting electrolyte, pH and instrumental parameters associated with the electrode response, including scan rate, accumulation potential and deposition time were optimized. The electrode platform demonstrated well resolved, reproducible peaks, with relative standard deviation (RSD) of 3.8% and detection limit (3S(b)/m) of 27.0 ng/mL. The sensor exhibited good D(4) detection and quantification in human blood plasma and urine samples.