Comparative neutralizing potencies of antibodies suggest conservation as well as mechanistic differences in human cytomegalovirus entry into epithelial and endothelial cells

Antibody neutralization of cytomegalovirus (CMV) entry into diverse cell types is a key consideration for development of vaccines and immunotherapeutics. CMV entry into fibroblasts differs significantly from entry into epithelial or endothelial cells: fibroblast entry is mediated by gB and gH/gL/gO,...

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Detalles Bibliográficos
Autores principales: Qi, Ying, He, Li, Cui, Xiaohong, Hertel, Laura, Freed, Daniel C., Fu, Tong-Ming, Kauvar, Lawrence M., McVoy, Michael A., Ruan, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144056/
https://www.ncbi.nlm.nih.gov/pubmed/32268919
http://dx.doi.org/10.1186/s12985-020-01320-2

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