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The Evolution of Pleconaril: Modified O-Alkyl Linker Analogs Have Biological Activity towards Coxsackievirus B3 Nancy

Coxsackieviruses type B are one of the most common causes of mild upper respiratory and gastrointestinal illnesses. At the time of writing, there are no approved drugs for effective antiviral treatment for Coxsackieviruses type B. We used the core-structure of pleconaril, a well-known antienterovira...

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Detalles Bibliográficos
Autores principales: Volobueva, Alexandrina, Egorova, Anna, Galochkina, Anastasia, Ekins, Sean, Zarubaev, Vladimir, Makarov, Vadim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144106/
https://www.ncbi.nlm.nih.gov/pubmed/32188089
http://dx.doi.org/10.3390/molecules25061345