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Multicomponent Domino Reaction in the Asymmetric Synthesis of Cyclopentan[c]pyran Core of Iridoid Natural Products

The asymmetric synthesis of a compound with the cyclopentan[c]pyran core of iridoid natural products in four steps and 40% overall yield is reported. Our methodology includes a one-pot tandem domino reaction which provides a trisubstituted cyclopentane with five new completely determined stereocente...

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Detalles Bibliográficos
Autores principales: Manchado, Alejandro, Ramos, Victoria Elena, Díez, David, Garrido, Narciso M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144114/
https://www.ncbi.nlm.nih.gov/pubmed/32182996
http://dx.doi.org/10.3390/molecules25061308