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Design, synthesis and anticancer activity of naphthoquinone derivatives

Basis on molecular docking and pharmacophore analysis of naphthoquinone moiety, a total of 23 compounds were designed and synthesised. With the help of reverse targets searching, anti-cancer activity was preliminarily evaluated, most of them are effective against some tumour cells, especially compou...

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Detalles Bibliográficos
Autores principales: Shen, Xiao-bao, Wang, Yang, Han, Xuan-zhen, Sheng, Liang-quan, Wu, Fu-fang, Liu, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144209/
https://www.ncbi.nlm.nih.gov/pubmed/32200656
http://dx.doi.org/10.1080/14756366.2020.1740693