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Design, synthesis and anticancer activity of naphthoquinone derivatives
Basis on molecular docking and pharmacophore analysis of naphthoquinone moiety, a total of 23 compounds were designed and synthesised. With the help of reverse targets searching, anti-cancer activity was preliminarily evaluated, most of them are effective against some tumour cells, especially compou...
Autores principales: | Shen, Xiao-bao, Wang, Yang, Han, Xuan-zhen, Sheng, Liang-quan, Wu, Fu-fang, Liu, Xinhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144209/ https://www.ncbi.nlm.nih.gov/pubmed/32200656 http://dx.doi.org/10.1080/14756366.2020.1740693 |
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