ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19

Smokers and those with COPD have increased airway expression of ACE-2, which is the entry receptor for the COVID-19 virus. This may explain the increased risk of severe COVID-19 in these subpopulations and highlight the importance of smoking cessation. https://bit.ly/3bC29es

Detalles Bibliográficos
Autores principales: Leung, Janice M., Yang, Chen X., Tam, Anthony, Shaipanich, Tawimas, Hackett, Tillie-Louise, Singhera, Gurpreet K., Dorscheid, Delbert R., Sin, Don D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2020
Materias:
Agora
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144263/
https://www.ncbi.nlm.nih.gov/pubmed/32269089
http://dx.doi.org/10.1183/13993003.00688-2020
Descripción
Sumario:Smokers and those with COPD have increased airway expression of ACE-2, which is the entry receptor for the COVID-19 virus. This may explain the increased risk of severe COVID-19 in these subpopulations and highlight the importance of smoking cessation. https://bit.ly/3bC29es

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