ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19

Smokers and those with COPD have increased airway expression of ACE-2, which is the entry receptor for the COVID-19 virus. This may explain the increased risk of severe COVID-19 in these subpopulations and highlight the importance of smoking cessation. https://bit.ly/3bC29es

Detalles Bibliográficos
Autores principales: Leung, Janice M., Yang, Chen X., Tam, Anthony, Shaipanich, Tawimas, Hackett, Tillie-Louise, Singhera, Gurpreet K., Dorscheid, Delbert R., Sin, Don D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2020
Materias:
Agora
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144263/
https://www.ncbi.nlm.nih.gov/pubmed/32269089
http://dx.doi.org/10.1183/13993003.00688-2020
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author Leung, Janice M.
Yang, Chen X.
Tam, Anthony
Shaipanich, Tawimas
Hackett, Tillie-Louise
Singhera, Gurpreet K.
Dorscheid, Delbert R.
Sin, Don D.
author_facet Leung, Janice M.
Yang, Chen X.
Tam, Anthony
Shaipanich, Tawimas
Hackett, Tillie-Louise
Singhera, Gurpreet K.
Dorscheid, Delbert R.
Sin, Don D.
author_sort Leung, Janice M.
collection PubMed
description Smokers and those with COPD have increased airway expression of ACE-2, which is the entry receptor for the COVID-19 virus. This may explain the increased risk of severe COVID-19 in these subpopulations and highlight the importance of smoking cessation. https://bit.ly/3bC29es
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spelling pubmed-71442632020-04-09 ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19 Leung, Janice M. Yang, Chen X. Tam, Anthony Shaipanich, Tawimas Hackett, Tillie-Louise Singhera, Gurpreet K. Dorscheid, Delbert R. Sin, Don D. Eur Respir J Agora Smokers and those with COPD have increased airway expression of ACE-2, which is the entry receptor for the COVID-19 virus. This may explain the increased risk of severe COVID-19 in these subpopulations and highlight the importance of smoking cessation. https://bit.ly/3bC29es European Respiratory Society 2020-05-14 /pmc/articles/PMC7144263/ /pubmed/32269089 http://dx.doi.org/10.1183/13993003.00688-2020 Text en Copyright ©ERS 2020 http://creativecommons.org/licenses/by-nc/4.0/This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.
spellingShingle Agora
Leung, Janice M.
Yang, Chen X.
Tam, Anthony
Shaipanich, Tawimas
Hackett, Tillie-Louise
Singhera, Gurpreet K.
Dorscheid, Delbert R.
Sin, Don D.
ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19
title ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19
title_full ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19
title_fullStr ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19
title_full_unstemmed ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19
title_short ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19
title_sort ace-2 expression in the small airway epithelia of smokers and copd patients: implications for covid-19
topic Agora
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144263/
https://www.ncbi.nlm.nih.gov/pubmed/32269089
http://dx.doi.org/10.1183/13993003.00688-2020
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