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Virtual screening for potential inhibitors of β(1,3)-D-glucan synthase as drug candidates against fungal cell wall

BACKGROUND: To enhance the outcome in patients with invasive candidiasis, initiation of an efficient antifungal treatment in a suitable dosage is necessary. Echinocandins (e.g. caspofungin) inhibit the enzyme β(1,3)-D-glucan synthase of the fungal cell wall. Compared to azoles and other antifungal a...

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Detalles Bibliográficos
Autores principales:	Farhadi, Zinat, Farhadi, Tayebeh, Hashemian, Seyed MohammadReza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144292/ https://www.ncbi.nlm.nih.gov/pubmed/32284908 http://dx.doi.org/10.1080/21556660.2020.1734010

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