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Supercritical CO(2) Extraction and Identification of Ginsenosides in Russian and North Korean Ginseng by HPLC with Tandem Mass Spectrometry

Ginseng roots, Panax ginseng C.A. Meyer, obtained from cultivated ginseng grown in the Kaesong province (North Korea) and Primorye (Russia) were extracted using the supercritical CO(2) extraction method. The extracts were subsequently analyzed by high-performance liquid chromatography with tandem ma...

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Detalles Bibliográficos
Autores principales: Razgonova, Mayya, Zakharenko, Alexander, Shin, Tai-Sun, Chung, Gyuhwa, Golokhvast, Kirill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144364/
https://www.ncbi.nlm.nih.gov/pubmed/32204525
http://dx.doi.org/10.3390/molecules25061407
Descripción
Sumario:Ginseng roots, Panax ginseng C.A. Meyer, obtained from cultivated ginseng grown in the Kaesong province (North Korea) and Primorye (Russia) were extracted using the supercritical CO(2) extraction method. The extracts were subsequently analyzed by high-performance liquid chromatography with tandem mass spectrometry identification. The results showed the spectral peaks of typical ginsenosides with some other minor groups, and major differences were observed between the spectra of the two ginseng samples. The use of a pressure of 400 bar and higher allowed an increase in the yield of ginsenosides in comparison with similar previous studies