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Bronquiectasias
Bronchiectasis is defined as irreversible dilatation of the bronchial lumen. Bronchiectasis not due to cystic fibrosis is the third most common chronic inflammatory disease of the airway, after asthma and chronic obstructive pulmonary disease (CPOD). The pathogenesis of the disease is characterised...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Espana
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144421/ https://www.ncbi.nlm.nih.gov/pubmed/32287909 http://dx.doi.org/10.1016/j.med.2018.09.010 |
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author | Romero, S. Graziani, D. |
author_facet | Romero, S. Graziani, D. |
author_sort | Romero, S. |
collection | PubMed |
description | Bronchiectasis is defined as irreversible dilatation of the bronchial lumen. Bronchiectasis not due to cystic fibrosis is the third most common chronic inflammatory disease of the airway, after asthma and chronic obstructive pulmonary disease (CPOD). The pathogenesis of the disease is characterised by chronic dilatation, with irreversible and usually progressive destruction of the bronchial wall as a consequence of the vicious pathogenic circle described by E. Cole, of infection, inflammation, injury to the mucociliary system, and cyclical repair of the airway. The disease can have different causes, and usually presents with cough and chronic expectoration, and repeated, acute, infectious exacerbations. Suspected diagnosis is clinical, and must be confirmed by high resolution computerised tomography. The treatment comprises diverse regimens aimed at controlling infection and bronchial inflammation. Nutritional aspects should be considered as part of treatment, as well as the management of secretions, muscle training and the management of complications and comorbidities. |
format | Online Article Text |
id | pubmed-7144421 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier Espana |
record_format | MEDLINE/PubMed |
spelling | pubmed-71444212020-04-09 Bronquiectasias Romero, S. Graziani, D. Medicine (Madr) Article Bronchiectasis is defined as irreversible dilatation of the bronchial lumen. Bronchiectasis not due to cystic fibrosis is the third most common chronic inflammatory disease of the airway, after asthma and chronic obstructive pulmonary disease (CPOD). The pathogenesis of the disease is characterised by chronic dilatation, with irreversible and usually progressive destruction of the bronchial wall as a consequence of the vicious pathogenic circle described by E. Cole, of infection, inflammation, injury to the mucociliary system, and cyclical repair of the airway. The disease can have different causes, and usually presents with cough and chronic expectoration, and repeated, acute, infectious exacerbations. Suspected diagnosis is clinical, and must be confirmed by high resolution computerised tomography. The treatment comprises diverse regimens aimed at controlling infection and bronchial inflammation. Nutritional aspects should be considered as part of treatment, as well as the management of secretions, muscle training and the management of complications and comorbidities. Elsevier Espana 2018-10 2018-09-28 /pmc/articles/PMC7144421/ /pubmed/32287909 http://dx.doi.org/10.1016/j.med.2018.09.010 Text en . Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Romero, S. Graziani, D. Bronquiectasias |
title | Bronquiectasias |
title_full | Bronquiectasias |
title_fullStr | Bronquiectasias |
title_full_unstemmed | Bronquiectasias |
title_short | Bronquiectasias |
title_sort | bronquiectasias |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144421/ https://www.ncbi.nlm.nih.gov/pubmed/32287909 http://dx.doi.org/10.1016/j.med.2018.09.010 |
work_keys_str_mv | AT romeros bronquiectasias AT grazianid bronquiectasias |