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Meeting the potential emergency global drug supply challenge of hydroxychloroquine for COVID-19
This paper provides an overview of the current global market and manufacturing landscape for hydroxychloroquine (HCQ). The capacity and capabilities of global producers to meet the potential demand for treating patients inflicted with COVID-19 by the novel corona virus SARS-CoV-2, should HCQ's...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier B.V.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144509/ https://www.ncbi.nlm.nih.gov/pubmed/32292908 http://dx.doi.org/10.1016/j.medidd.2020.100036 |
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author | Zhang, Tony Y. Zhong, Boyu |
author_facet | Zhang, Tony Y. Zhong, Boyu |
author_sort | Zhang, Tony Y. |
collection | PubMed |
description | This paper provides an overview of the current global market and manufacturing landscape for hydroxychloroquine (HCQ). The capacity and capabilities of global producers to meet the potential demand for treating patients inflicted with COVID-19 by the novel corona virus SARS-CoV-2, should HCQ's efficacy be established by more definitive clinical trials, is also assessed. Given the large existing manufacturing base and abundance of raw materials for HCQ, the supply challenge can be met with considerable efforts and international cooperation. Preemptive and coordinated emergency efforts among global governments, regulatory agencies, chemical and pharmaceutical industries are imperative for meeting the potential surge in demand. |
format | Online Article Text |
id | pubmed-7144509 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Author(s). Published by Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71445092020-04-09 Meeting the potential emergency global drug supply challenge of hydroxychloroquine for COVID-19 Zhang, Tony Y. Zhong, Boyu Med Drug Discov Article This paper provides an overview of the current global market and manufacturing landscape for hydroxychloroquine (HCQ). The capacity and capabilities of global producers to meet the potential demand for treating patients inflicted with COVID-19 by the novel corona virus SARS-CoV-2, should HCQ's efficacy be established by more definitive clinical trials, is also assessed. Given the large existing manufacturing base and abundance of raw materials for HCQ, the supply challenge can be met with considerable efforts and international cooperation. Preemptive and coordinated emergency efforts among global governments, regulatory agencies, chemical and pharmaceutical industries are imperative for meeting the potential surge in demand. The Author(s). Published by Elsevier B.V. 2020-03 2020-04-09 /pmc/articles/PMC7144509/ /pubmed/32292908 http://dx.doi.org/10.1016/j.medidd.2020.100036 Text en © 2020 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Zhang, Tony Y. Zhong, Boyu Meeting the potential emergency global drug supply challenge of hydroxychloroquine for COVID-19 |
title | Meeting the potential emergency global drug supply challenge of hydroxychloroquine for COVID-19 |
title_full | Meeting the potential emergency global drug supply challenge of hydroxychloroquine for COVID-19 |
title_fullStr | Meeting the potential emergency global drug supply challenge of hydroxychloroquine for COVID-19 |
title_full_unstemmed | Meeting the potential emergency global drug supply challenge of hydroxychloroquine for COVID-19 |
title_short | Meeting the potential emergency global drug supply challenge of hydroxychloroquine for COVID-19 |
title_sort | meeting the potential emergency global drug supply challenge of hydroxychloroquine for covid-19 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144509/ https://www.ncbi.nlm.nih.gov/pubmed/32292908 http://dx.doi.org/10.1016/j.medidd.2020.100036 |
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