Transcriptional profiling identifies caspase-1 as a T cell–intrinsic regulator of Th17 differentiation

Dendritic cells (DCs) are critical for the differentiation of pathogen-specific CD4 T cells. However, to what extent innate cues from DCs dictate transcriptional changes in T cells remains elusive. Here, we used DCs stimulated with specific pathogens to prime CD4 T cells in vitro and found that thes...

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Detalles Bibliográficos
Autores principales: Gao, Yajing, Deason, Krystin, Jain, Aakanksha, Irizarry-Caro, Ricardo A., Dozmorov, Igor, Coughlin, Laura A., Rauch, Isabella, Evers, Bret M., Koh, Andrew Y., Wakeland, Edward K., Pasare, Chandrashekhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144520/
https://www.ncbi.nlm.nih.gov/pubmed/31967646
http://dx.doi.org/10.1084/jem.20190476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144520/
https://www.ncbi.nlm.nih.gov/pubmed/31967646
http://dx.doi.org/10.1084/jem.20190476

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