A critical role for plasminogen in inflammation

Plasminogen and its active form, plasmin, have diverse functions related to the inflammatory response in mammals. Due to these roles in inflammation, plasminogen has been implicated in the progression of a wide range of diseases with an inflammatory component. In this review, we discuss the function...

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Detalles Bibliográficos
Autores principales: Baker, Sarah K., Strickland, Sidney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144526/
https://www.ncbi.nlm.nih.gov/pubmed/32159743
http://dx.doi.org/10.1084/jem.20191865
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author Baker, Sarah K.
Strickland, Sidney
author_facet Baker, Sarah K.
Strickland, Sidney
author_sort Baker, Sarah K.
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description Plasminogen and its active form, plasmin, have diverse functions related to the inflammatory response in mammals. Due to these roles in inflammation, plasminogen has been implicated in the progression of a wide range of diseases with an inflammatory component. In this review, we discuss the functions of plasminogen in inflammatory regulation and how this system plays a role in the pathogenesis of diseases spanning organ systems throughout the body.
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spelling pubmed-71445262020-10-06 A critical role for plasminogen in inflammation Baker, Sarah K. Strickland, Sidney J Exp Med Review Plasminogen and its active form, plasmin, have diverse functions related to the inflammatory response in mammals. Due to these roles in inflammation, plasminogen has been implicated in the progression of a wide range of diseases with an inflammatory component. In this review, we discuss the functions of plasminogen in inflammatory regulation and how this system plays a role in the pathogenesis of diseases spanning organ systems throughout the body. Rockefeller University Press 2020-03-11 /pmc/articles/PMC7144526/ /pubmed/32159743 http://dx.doi.org/10.1084/jem.20191865 Text en © 2020 Baker and Strickland http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Review
Baker, Sarah K.
Strickland, Sidney
A critical role for plasminogen in inflammation
title A critical role for plasminogen in inflammation
title_full A critical role for plasminogen in inflammation
title_fullStr A critical role for plasminogen in inflammation
title_full_unstemmed A critical role for plasminogen in inflammation
title_short A critical role for plasminogen in inflammation
title_sort critical role for plasminogen in inflammation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144526/
https://www.ncbi.nlm.nih.gov/pubmed/32159743
http://dx.doi.org/10.1084/jem.20191865
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