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Essential cell-extrinsic requirement for PDIA6 in lymphoid and myeloid development

In a forward genetic screen of N-ethyl-N-nitrosourea (ENU)–induced mutant mice for aberrant immune function, we identified mice with a syndromic disorder marked by growth retardation, diabetes, premature death, and severe lymphoid and myeloid hypoplasia together with diminished T cell–independent (T...

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Detalles Bibliográficos
Autores principales: Choi, Jin Huk, Zhong, Xue, Zhang, Zhao, Su, Lijing, McAlpine, William, Misawa, Takuma, Liao, Tzu-Chieh, Zhan, Xiaoming, Russell, Jamie, Ludwig, Sara, Li, Xiaohong, Tang, Miao, Anderton, Priscilla, Moresco, Eva Marie Y., Beutler, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144532/
https://www.ncbi.nlm.nih.gov/pubmed/31985756
http://dx.doi.org/10.1084/jem.20190006

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