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Microglia in Alzheimer’s disease: Local heroes!

In this issue of JEM, Reed-Geaghan et al. (https://doi.org/10.1084/jem.20191374) address the long-standing question about the primary source of myeloid cells located at β-amyloid deposits. Using genetic labeling experiments, the authors identify resident microglia as the only myeloid cells present a...

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Detalles Bibliográficos
Autores principales: Villacampa, Nàdia, Heneka, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144535/
https://www.ncbi.nlm.nih.gov/pubmed/32126139
http://dx.doi.org/10.1084/jem.20192311
Descripción
Sumario:In this issue of JEM, Reed-Geaghan et al. (https://doi.org/10.1084/jem.20191374) address the long-standing question about the primary source of myeloid cells located at β-amyloid deposits. Using genetic labeling experiments, the authors identify resident microglia as the only myeloid cells present at β-amyloid deposits.