Cargando…

Evodiamine Mitigates Cellular Growth and Promotes Apoptosis by Targeting the c-Met Pathway in Prostate Cancer Cells

Evodiamine (EVO) is an indoloquinazoline alkaloid that exerts its various anti-oncogenic actions by blocking phosphatidylinositol-3-kinase/protein kinase B (PI3K/Akt), mitogen-activated protein kinase (MAPK), c-Met, and nuclear factor kappa B (NF-κB) signaling pathways, thus leading to apoptosis of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hwang, Sun Tae, Um, Jae-Young, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Narula, Acharan S., Namjoshi, Ojas A., Blough, Bruce E., Ahn, Kwang Seok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144730/ https://www.ncbi.nlm.nih.gov/pubmed/32183146 http://dx.doi.org/10.3390/molecules25061320

Ejemplares similares

Identification of Matrine as a Novel Regulator of the CXCR4 Signaling Axis in Tumor Cells
por: Jung, Young Yun, et al.
Publicado: (2020)

Anti-myeloma Effects of Icariin Are Mediated Through the Attenuation of JAK/STAT3-Dependent Signaling Cascade
por: Jung, Young Yun, et al.
Publicado: (2018)

Oxymatrine Attenuates Tumor Growth and Deactivates STAT5 Signaling in a Lung Cancer Xenograft Model
por: Jung, Young Yun, et al.
Publicado: (2019)

2,3,5,6-Tetramethylpyrazine Targets Epithelial-Mesenchymal Transition by Abrogating Manganese Superoxide Dismutase Expression and TGFβ-Driven Signaling Cascades in Colon Cancer Cells
por: Jung, Young Yun, et al.
Publicado: (2022)

Fangchinoline, a Bisbenzylisoquinoline Alkaloid can Modulate Cytokine-Impelled Apoptosis via the Dual Regulation of NF-κB and AP-1 Pathways
por: Jung, Young Yun, et al.
Publicado: (2019)

2,5-Dihydroxyacetophenone Induces Apoptosis of Multiple Myeloma Cells by Regulating the MAPK Activation Pathway
por: Ko, Jeong-Hyeon, et al.
Publicado: (2017)

Leelamine Modulates STAT5 Pathway Causing Both Autophagy and Apoptosis in Chronic Myelogenous Leukemia Cells
por: Jung, Young Yun, et al.
Publicado: (2022)

Procaine Abrogates the Epithelial-Mesenchymal Transition Process through Modulating c-Met Phosphorylation in Hepatocellular Carcinoma
por: Yang, Min Hee, et al.
Publicado: (2022)

Euphorbiasteroid Abrogates EGFR and Wnt/β-Catenin Signaling in Non-Small-Cell Lung Cancer Cells to Impart Anticancer Activity
por: Kim, Na Young, et al.
Publicado: (2022)

Attenuation of STAT3 Signaling Cascade by Daidzin Can Enhance the Apoptotic Potential of Bortezomib against Multiple Myeloma
por: Yang, Min Hee, et al.
Publicado: (2019)

Evodiamine activates cellular apoptosis through suppressing PI3K/AKT and activating MAPK in glioma
por: Wang, Rong, et al.
Publicado: (2018)

In vitro cellular uptake of evodiamine and rutaecarpine using a microemulsion
por: Zhang, Yong-Tai, et al.
Publicado: (2012)

The natural analgesic conolidine targets the newly identified opioid scavenger ACKR3/CXCR7
por: Szpakowska, Martyna, et al.
Publicado: (2021)

Inhibitory effects of evodiamine on human osteosarcoma cell proliferation and apoptosis
por: BAI, XIAODONG, et al.
Publicado: (2015)

Celastrol Alleviates Gamma Irradiation-Induced Damage by Modulating Diverse Inflammatory Mediators
por: Wang, Hong, et al.
Publicado: (2020)

Punicalagin promotes the apoptosis in human cervical cancer (ME-180) cells through mitochondrial pathway and by inhibiting the NF-kB signaling pathway
por: Zhang, Li, et al.
Publicado: (2020)

Formononetin Regulates Multiple Oncogenic Signaling Cascades and Enhances Sensitivity to Bortezomib in a Multiple Myeloma Mouse Model
por: Kim, Chulwon, et al.
Publicado: (2019)

Isorhynchophylline, a Potent Plant Alkaloid, Induces Apoptotic and Anti-Metastatic Effects in Human Hepatocellular Carcinoma Cells through the Modulation of Diverse Cell Signaling Cascades
por: Lee, Hanwool, et al.
Publicado: (2017)

Berbamine Analogs Exhibit Differential Protective Effects From Aminoglycoside-Induced Hair Cell Death
por: Hudson, Alexandria M., et al.
Publicado: (2020)

Ginkgolic Acid C 17:1, Derived from Ginkgo biloba Leaves, Suppresses Constitutive and Inducible STAT3 Activation through Induction of PTEN and SHP-1 Tyrosine Phosphatase
por: Baek, Seung Ho, et al.
Publicado: (2017)

Activation of JNK Contributes to Evodiamine-Induced Apoptosis and G(2)/M Arrest in Human Colorectal Carcinoma Cells: A Structure-Activity Study of Evodiamine
por: Chien, Chih-Chiang, et al.
Publicado: (2014)

Antiproliferative Activity and Cellular Uptake of Evodiamine and Rutaecarpine Based on 3D Tumor Models
por: Guo, Hui, et al.
Publicado: (2016)

Evaluation of the Cardiotoxicity of Evodiamine In Vitro and In Vivo
por: Yang, Weifeng, et al.
Publicado: (2017)

Mycelium of fungi isolated from mouldy foods inhibits Staphylococcus aureus including MRSA – A rationale for the re-introduction of mycotherapy?
por: Alnaimat, Sulaiman, et al.
Publicado: (2015)

Evodiamine Induces Apoptosis and Inhibits Migration of HCT-116 Human Colorectal Cancer Cells
por: Zhao, Lv-Cui, et al.
Publicado: (2015)

Evodiamine Reduces Caffeine-Induced Sleep Disturbances and Excitation in Mice
por: Ko, Yong-Hyun, et al.
Publicado: (2018)

The IκB Kinase Inhibitor ACHP Targets the STAT3 Signaling Pathway in Human Non-Small Cell Lung Carcinoma Cells
por: Lee, Jong Hyun, et al.
Publicado: (2019)

3-Formylchromone Counteracts STAT3 Signaling Pathway by Elevating SHP-2 Expression in Hepatocellular Carcinoma
por: Mohan, Chakrabhavi Dhananjaya, et al.
Publicado: (2021)

Anti-neoplastic Effect of Ginkgolide C through Modulating c-Met Phosphorylation in Hepatocellular Carcinoma Cells
por: Yang, Min Hee, et al.
Publicado: (2020)

Preparation of Evodiamine Solid Dispersions and Its Pharmacokinetics
por: Xu, H., et al.
Publicado: (2011)

Antiproliferative Effects of Alkaloid Evodiamine and Its Derivatives
por: Hu, Xu, et al.
Publicado: (2018)

Pharmacological Actions of Multi-Target-Directed Evodiamine
por: Yu, Hui, et al.
Publicado: (2013)

Evodiamine Selectively Inhibits Multiple Myeloma Cell Growth by Triggering Activation of Intrinsic Apoptosis Pathway
por: Fang, Qing, et al.
Publicado: (2019)

An overview of the anti-cancer actions of Tanshinones, derived from Salvia miltiorrhiza (Danshen)
por: Naz, Irum, et al.
Publicado: (2020)

Development of a Model System to Study Expression Profile of RAC2 Gene in Breast Cancer MDA-MB-231 Cell Line
por: Sivakumar Harish, Thogulva, et al.
Publicado: (2022)

Evodiamine induces reactive oxygen species-dependent apoptosis and necroptosis in human melanoma A-375 cells
por: Liu, Ning, et al.
Publicado: (2020)

Induction of Apoptosis and Effect on the FAK/AKT/mTOR Signal Pathway by Evodiamine in Gastric Cancer Cells
por: Yang, Ji Yeong, et al.
Publicado: (2022)

Enhanced transdermal delivery of evodiamine and rutaecarpine using microemulsion
por: Zhang, Yong-Tai, et al.
Publicado: (2011)

Preventive Effects of Evodiamine on Dexamethasone-Induced Osteoporosis in Zebrafish
por: Yin, Heng, et al.
Publicado: (2019)

A Critical YAP in Malignancy of HCC Is Regulated by Evodiamine
por: Yun, Un-Jung, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_b66pa9p32mervaui15gpninhto