Novel decoy cellular vaccine strategy utilizing transgenic antigen-expressing cells as immune presenter and adjuvant in vaccine prototype against SARS-CoV-2 virus

A novel approach modifying cells to express viral markers to elicit protective immunity responses (decoy cellular vaccination) in the prevention of COVID-19 disease is currently being explored. Our approach entails utilizing SARS-CoV-2 Spike antigen-expressing, non-replicating cells as carriers and...

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Detalles Bibliográficos
Autores principales: Ji, Henry, Yan, Ying, Ding, Beibei, Guo, Wenzhong, Brunswick, Mark, Niethammer, Andreas, SooHoo, Williams, Smith, Robin, Nahama, Alexis, Zhang, Yanliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144842/
https://www.ncbi.nlm.nih.gov/pubmed/32289117
http://dx.doi.org/10.1016/j.medidd.2020.100026

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