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Reducing INS-IGF1 signaling protects against non-cell autonomous vesicle rupture caused by SNCA spreading
Aging is associated with a gradual decline of cellular proteostasis, giving rise to devastating protein misfolding diseases, such as Alzheimer disease (AD) or Parkinson disease (PD). These diseases often exhibit a complex pathology involving non-cell autonomous proteotoxic effects, which are still p...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144869/ https://www.ncbi.nlm.nih.gov/pubmed/31354022 http://dx.doi.org/10.1080/15548627.2019.1643657 |