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Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B

DNA methyltransferases are primary enzymes for cytosine methylation at CpG sites of epigenetic gene regulation in mammals. De novo methyltransferases DNMT3A and DNMT3B create DNA methylation patterns during development, but how they differentially implement genomic DNA methylation patterns is poorly...

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Detalles Bibliográficos
Autores principales: Lin, Chien-Chu, Chen, Yi-Ping, Yang, Wei-Zen, Shen, James C K, Yuan, Hanna S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144912/
https://www.ncbi.nlm.nih.gov/pubmed/32083663
http://dx.doi.org/10.1093/nar/gkaa111