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Oplr16 serves as a novel chromatin factor to control stem cell fate by modulating pluripotency-specific chromosomal looping and TET2-mediated DNA demethylation

Formation of a pluripotency-specific chromatin network is a critical event in reprogramming somatic cells into pluripotent status. To characterize the regulatory components in this process, we used ‘chromatin RNA in situ reverse transcription sequencing’ (CRIST-seq) to profile RNA components that in...

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Detalles Bibliográficos
Autores principales: Jia, Lin, Wang, Yichen, Wang, Cong, Du, Zhonghua, Zhang, Shilin, Wen, Xue, Zhou, Lei, Li, Hui, Chen, Huiling, Li, Dan, Zhang, Songling, Li, Wei, Xu, Wei, Hoffman, Andrew R, Cui, Jiuwei, Hu, Ji-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144914/
https://www.ncbi.nlm.nih.gov/pubmed/32055844
http://dx.doi.org/10.1093/nar/gkaa097

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