Cargando…
The m(6)A reader YTHDF1 promotes ovarian cancer progression via augmenting EIF3C translation
N (6)-Methyladenosine (m(6)A) is the most abundant RNA modification in mammal mRNAs and increasing evidence suggests the key roles of m(6)A in human tumorigenesis. However, whether m(6)A, especially its ‘reader’ YTHDF1, targets a gene involving in protein translation and thus affects overall protein...
Autores principales: | Liu, Tao, Wei, Qinglv, Jin, Jing, Luo, Qingya, Liu, Yi, Yang, Yu, Cheng, Chunming, Li, Lanfang, Pi, Jingnan, Si, Yanmin, Xiao, Hualiang, Li, Li, Rao, Shuan, Wang, Fang, Yu, Jianhua, Yu, Jia, Zou, Dongling, Yi, Ping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144925/ https://www.ncbi.nlm.nih.gov/pubmed/31996915 http://dx.doi.org/10.1093/nar/gkaa048 |
Ejemplares similares
-
The m(6)A reader YTHDF1 regulates axon guidance through translational control of Robo3.1 expression
por: Zhuang, Mengru, et al.
Publicado: (2019) -
SUMOylation of YTHDF2 promotes mRNA degradation and cancer progression by increasing its binding affinity with m(6)A-modified mRNAs
por: Hou, Guofang, et al.
Publicado: (2021) -
Novel mechanisms of eIF2B action and regulation by eIF2α phosphorylation
por: Bogorad, Andrew M., et al.
Publicado: (2017) -
The domains of yeast eIF4G, eIF4E and the cap fine-tune eIF4A activities through an intricate network of stimulatory and inhibitory effects
por: Krause, Linda, et al.
Publicado: (2022) -
Translational fidelity screens in mammalian cells reveal eIF3 and eIF4G2 as regulators of start codon selectivity
por: She, Richard, et al.
Publicado: (2023)