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Inhibition of cytoplasmic cap methylation identifies 5′ TOP mRNAs as recapping targets and reveals recapping sites downstream of native 5′ ends
Cap homeostasis is the cyclical process of decapping and recapping that maintains the translation and stability of a subset of the transcriptome. Previous work showed levels of some recapping targets decline following transient expression of an inactive form of RNMT (ΔN-RNMT), likely due to degradat...
Autores principales: | del Valle Morales, Daniel, Trotman, Jackson B, Bundschuh, Ralf, Schoenberg, Daniel R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144985/ https://www.ncbi.nlm.nih.gov/pubmed/31996904 http://dx.doi.org/10.1093/nar/gkaa046 |
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