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Blind estimation and correction of microarray batch effect
Microarray batch effect (BE) has been the primary bottleneck for large-scale integration of data from multiple experiments. Current BE correction methods either need known batch identities (ComBat) or have the potential to overcorrect, by removing true but unknown biological differences (Surrogate V...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145015/ https://www.ncbi.nlm.nih.gov/pubmed/32271844 http://dx.doi.org/10.1371/journal.pone.0231446 |