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A population-specific low-frequency variant of SLC22A12 (p.W258*) explains nearby genome-wide association signals for serum uric acid concentrations among Koreans

Prolonged hyperuricemia is a cause of gout and an independent risk factor for chronic health conditions including diabetes and chronic kidney diseases. Genome-wide association studies (GWASs) for serum uric acid (SUA) concentrations have repeatedly confirmed genetic loci including those encoding uri...

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Detalles Bibliográficos
Autores principales:	Im, Sun-Wha, Chae, Jeesoo, Son, Ho-Young, Cho, Belong, Kim, Jong-Il, Park, Jin-Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145145/ https://www.ncbi.nlm.nih.gov/pubmed/32271837 http://dx.doi.org/10.1371/journal.pone.0231336

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