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Unique Roles for Streptococcus pneumoniae Phosphodiesterase 2 in Cyclic di-AMP Catabolism and Macrophage Responses

Cyclic di-AMP (c-di-AMP) is an important signaling molecule for pneumococci, and as a uniquely prokaryotic product it can be recognized by mammalian cells as a danger signal that triggers innate immunity. Roles of c-di-AMP in directing host responses during pneumococcal infection are only beginning...

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Detalles Bibliográficos
Autores principales:	Wooten, Alicia K., Shenoy, Anukul T., Arafa, Emad I., Akiyama, Hisashi, Martin, Ian M. C., Jones, Matthew R., Quinton, Lee J., Gummuluru, Suryaram, Bai, Guangchun, Mizgerd, Joseph P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145409/ https://www.ncbi.nlm.nih.gov/pubmed/32300347 http://dx.doi.org/10.3389/fimmu.2020.00554

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