Cargando…

Cooperative enzymatic control of N-acyl amino acids by PM20D1 and FAAH

The N-acyl amino acids are a family of bioactive lipids with pleiotropic physiologic functions, including in energy homeostasis. Their endogenous levels are regulated by an extracellular mammalian N-acyl amino acid synthase/hydrolase called PM20D1 (peptidase M20 domain containing 1). Using an activi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Joon T, Terrell, Stephanie M, Li, Veronica L, Wei, Wei, Fischer, Curt R, Long, Jonathan Z
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145423/ https://www.ncbi.nlm.nih.gov/pubmed/32271712 http://dx.doi.org/10.7554/eLife.55211

Ejemplares similares

SIRT2 and lysine fatty acylation regulate the transforming activity of K-Ras4a
por: Jing, Hui, et al.
Publicado: (2017)

Acyl chain asymmetry and polyunsaturation of brain phospholipids facilitate membrane vesiculation without leakage
por: Manni, Marco M, et al.
Publicado: (2018)

Non-enzymatic primer extension with strand displacement
por: Zhou, Lijun, et al.
Publicado: (2019)

Glycine acylation and trafficking of a new class of bacterial lipoprotein by a composite secretion system
por: Icke, Christopher, et al.
Publicado: (2021)

Structural basis for an unprecedented enzymatic alkylation in cylindrocyclophane biosynthesis
por: Braffman, Nathaniel R, et al.
Publicado: (2022)

Nitrogenase resurrection and the evolution of a singular enzymatic mechanism
por: Garcia, Amanda K, et al.
Publicado: (2023)

A novel fold for acyltransferase-3 (AT3) proteins provides a framework for transmembrane acyl-group transfer
por: Newman, Kahlan E, et al.
Publicado: (2023)

Divergent acyl carrier protein decouples mitochondrial Fe-S cluster biogenesis from fatty acid synthesis in malaria parasites
por: Falekun, Seyi, et al.
Publicado: (2021)

A universal pocket in fatty acyl-AMP ligases ensures redirection of fatty acid pool away from coenzyme A-based activation
por: Patil, Gajanan S, et al.
Publicado: (2021)

Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2
por: Long, Yicheng, et al.
Publicado: (2017)

Intracellular complexities of acquiring a new enzymatic function revealed by mass-randomisation of active-site residues
por: Hall, Kelsi R, et al.
Publicado: (2020)

Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPARγ
por: Shang, Jinsai, et al.
Publicado: (2018)

Allosteric cooperation in β-lactam binding to a non-classical transpeptidase
por: Ahmad, Nazia, et al.
Publicado: (2022)

Diverse functions of homologous actin isoforms are defined by their nucleotide, rather than their amino acid sequence
por: Vedula, Pavan, et al.
Publicado: (2017)

The DREAM complex through its subunit Lin37 cooperates with Rb to initiate quiescence
por: Mages, Christina FS, et al.
Publicado: (2017)

An H3K9 methylation-dependent protein interaction regulates the non-enzymatic functions of a putative histone demethylase
por: Raiymbek, Gulzhan, et al.
Publicado: (2020)

Creation of photocyclic vertebrate rhodopsin by single amino acid substitution
por: Sakai, Kazumi, et al.
Publicado: (2022)

The cooperative binding of TDP-43 to GU-rich RNA repeats antagonizes TDP-43 aggregation
por: Rengifo-Gonzalez, Juan Carlos, et al.
Publicado: (2021)

Ablation of PM20D1 reveals N-acyl amino acid control of metabolism and nociception
por: Long, Jonathan Z., et al.
Publicado: (2018)

Coevolution-based inference of amino acid interactions underlying protein function
por: Salinas, Victor H, et al.
Publicado: (2018)

Cooperation among c-subunits of F(o)F(1)-ATP synthase in rotation-coupled proton translocation
por: Mitome, Noriyo, et al.
Publicado: (2022)

Doublecortin engages the microtubule lattice through a cooperative binding mode involving its C-terminal domain
por: Rafiei, Atefeh, et al.
Publicado: (2022)

Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis
por: Apiz Saab, Juan J, et al.
Publicado: (2023)

Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism
por: Ryan, Dylan Gerard, et al.
Publicado: (2021)

An improved fluorescent noncanonical amino acid for measuring conformational distributions using time-resolved transition metal ion FRET
por: Zagotta, William N, et al.
Publicado: (2021)

The mitochondrial acyl carrier protein (ACP) coordinates mitochondrial fatty acid synthesis with iron sulfur cluster biogenesis
por: Van Vranken, Jonathan G, et al.
Publicado: (2016)

A third-generation dispersion and third-generation hydrogen bonding corrected PM6 method: PM6-D3H+
por: Kromann, Jimmy C., et al.
Publicado: (2014)

Amino-acyl tXNA as inhibitors or amino acid donors in peptide synthesis
por: Rietmeyer, Lauriane, et al.
Publicado: (2022)

SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation
por: Zhang, Xiaoyu, et al.
Publicado: (2017)

Genetic analysis reveals functions of atypical polyubiquitin chains
por: Meza Gutierrez, Fernando, et al.
Publicado: (2018)

N (4)-acyl-2′-deoxycytidine-5′-triphosphates for the enzymatic synthesis of modified DNA
por: Jakubovska, Jevgenija, et al.
Publicado: (2018)

Enhancement of E. coli acyl-CoA synthetase FadD activity on medium chain fatty acids
por: Ford, Tyler J., et al.
Publicado: (2015)

Protein visualization and manipulation in Drosophila through the use of epitope tags recognized by nanobodies
por: Xu, Jun, et al.
Publicado: (2022)

Systematic bioprospection for cellulolytic actinomycetes in the Chihuahuan Desert: isolation and enzymatic profiling
por: Escudero-Agudelo, Janneth, et al.
Publicado: (2023)

The use of synthetic agonists of quorum sensing N- acyl homoserine lactone pathway improves the bioleaching ability in Acidithiobacillus and Pseudomonas bacteria
por: Caicedo, Juan Carlos, et al.
Publicado: (2022)

The inner mechanics of rhodopsin guanylyl cyclase during cGMP-formation revealed by real-time FTIR spectroscopy
por: Fischer, Paul, et al.
Publicado: (2021)

Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks
por: Zhao, Suwen, et al.
Publicado: (2014)

UBE2G1 governs the destruction of cereblon neomorphic substrates
por: Lu, Gang, et al.
Publicado: (2018)

An efficient method for saliva collection from mature pigs to determine their enzymatic and electrolytic profiles
por: AKHTAR, Nadeem, et al.
Publicado: (2017)

Comprehensive exploration of the translocation, stability and substrate recognition requirements in VIM-2 lactamase
por: Chen, John Z, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_9bpmh15i6q7s4u4k1olreb5qa4