Cargando…

Repair of Acute Type-A Aortic Dissection in the Present Era: Outcomes and Controversies

Acute Type-A aortic dissection (AAAD) remains a surgical emergency with a relatively high operative mortality despite advances in medical and surgical management over the past three decades. In spite of the severity of disease, there is a paucity of studies reviewing key controversies surrounding AA...

Descripción completa

Detalles Bibliográficos
Autores principales: Moeller, Ellie, Nores, Marcos, Stamou, Sotiris C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical Publishers 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145439/
https://www.ncbi.nlm.nih.gov/pubmed/32272487
http://dx.doi.org/10.1055/s-0039-3401810
_version_ 1783520000743571456
author Moeller, Ellie
Nores, Marcos
Stamou, Sotiris C.
author_facet Moeller, Ellie
Nores, Marcos
Stamou, Sotiris C.
author_sort Moeller, Ellie
collection PubMed
description Acute Type-A aortic dissection (AAAD) remains a surgical emergency with a relatively high operative mortality despite advances in medical and surgical management over the past three decades. In spite of the severity of disease, there is a paucity of studies reviewing key controversies surrounding AAAD repair and management. A systematic literature search was performed using Cochrane review and PubMed bibliography review. Abstracts were first reviewed for general pertinence and then articles were reviewed in full. Literature review indicates that use of moderate hypothermia and antegrade cerebral perfusion is a safe alternative to deep hypothermia. In hemodynamically stable patients, axillary cannulation may be substituted for femoral cannulation. With regard to the technical aspects of repair, preserving the aortic root whenever possible and performing the distal anastomosis with the open distal technique rather than with the clamp on is the preferred approach. In patients with a patent false lumen, close monitoring is indicated. As demonstrated by the literature, significant improvement of early and late mortality over the past years has occurred in patients presenting with AAAD. Repair of acute Type-A aortic dissection remains a challenge with high operative mortality; however, improvement of surgical techniques and management have resulted in improvement of early and late clinical outcomes.
format Online
Article
Text
id pubmed-7145439
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Thieme Medical Publishers
record_format MEDLINE/PubMed
spelling pubmed-71454392020-04-10 Repair of Acute Type-A Aortic Dissection in the Present Era: Outcomes and Controversies Moeller, Ellie Nores, Marcos Stamou, Sotiris C. Aorta (Stamford) Acute Type-A aortic dissection (AAAD) remains a surgical emergency with a relatively high operative mortality despite advances in medical and surgical management over the past three decades. In spite of the severity of disease, there is a paucity of studies reviewing key controversies surrounding AAAD repair and management. A systematic literature search was performed using Cochrane review and PubMed bibliography review. Abstracts were first reviewed for general pertinence and then articles were reviewed in full. Literature review indicates that use of moderate hypothermia and antegrade cerebral perfusion is a safe alternative to deep hypothermia. In hemodynamically stable patients, axillary cannulation may be substituted for femoral cannulation. With regard to the technical aspects of repair, preserving the aortic root whenever possible and performing the distal anastomosis with the open distal technique rather than with the clamp on is the preferred approach. In patients with a patent false lumen, close monitoring is indicated. As demonstrated by the literature, significant improvement of early and late mortality over the past years has occurred in patients presenting with AAAD. Repair of acute Type-A aortic dissection remains a challenge with high operative mortality; however, improvement of surgical techniques and management have resulted in improvement of early and late clinical outcomes. Thieme Medical Publishers 2020-04-09 /pmc/articles/PMC7145439/ /pubmed/32272487 http://dx.doi.org/10.1055/s-0039-3401810 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Moeller, Ellie
Nores, Marcos
Stamou, Sotiris C.
Repair of Acute Type-A Aortic Dissection in the Present Era: Outcomes and Controversies
title Repair of Acute Type-A Aortic Dissection in the Present Era: Outcomes and Controversies
title_full Repair of Acute Type-A Aortic Dissection in the Present Era: Outcomes and Controversies
title_fullStr Repair of Acute Type-A Aortic Dissection in the Present Era: Outcomes and Controversies
title_full_unstemmed Repair of Acute Type-A Aortic Dissection in the Present Era: Outcomes and Controversies
title_short Repair of Acute Type-A Aortic Dissection in the Present Era: Outcomes and Controversies
title_sort repair of acute type-a aortic dissection in the present era: outcomes and controversies
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145439/
https://www.ncbi.nlm.nih.gov/pubmed/32272487
http://dx.doi.org/10.1055/s-0039-3401810
work_keys_str_mv AT moellerellie repairofacutetypeaaorticdissectioninthepresenteraoutcomesandcontroversies
AT noresmarcos repairofacutetypeaaorticdissectioninthepresenteraoutcomesandcontroversies
AT stamousotirisc repairofacutetypeaaorticdissectioninthepresenteraoutcomesandcontroversies