Cargando…

ChiTaRS 5.0: the comprehensive database of chimeric transcripts matched with druggable fusions and 3D chromatin maps

Chimeric RNA transcripts are formed when exons from two genes fuse together, often due to chromosomal translocations, transcriptional errors or trans-splicing effect. While these chimeric RNAs produce functional proteins only in certain cases, they play a significant role in disease phenotyping and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Balamurali, Deepak, Gorohovski, Alessandro, Detroja, Rajesh, Palande, Vikrant, Raviv-Shay, Dorith, Frenkel-Morgenstern, Milana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Database Issue
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145514/ https://www.ncbi.nlm.nih.gov/pubmed/31747015 http://dx.doi.org/10.1093/nar/gkz1025

Ejemplares similares

ChiTaRS-3.1—the enhanced chimeric transcripts and RNA-seq database matched with protein–protein interactions
por: Gorohovski, Alessandro, et al.
Publicado: (2017)

ChiTaRS 2.1—an improved database of the chimeric transcripts and RNA-seq data with novel sense–antisense chimeric RNA transcripts
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2014)

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2013)

ChiTaH: a fast and accurate tool for identifying known human chimeric sequences from high-throughput sequencing data
por: Detroja, Rajesh, et al.
Publicado: (2021)

Design principles of gene evolution for niche adaptation through changes in protein–protein interaction networks
por: Carmi, Gon, et al.
Publicado: (2020)

Computational analysis of sense-antisense chimeric transcripts reveals their potential regulatory features and the landscape of expression in human cells
por: Mukherjee, Sumit, et al.
Publicado: (2021)

Detection of gene mutations and gene–gene fusions in circulating cell‐free DNA of glioblastoma patients: an avenue for clinically relevant diagnostic analysis
por: Palande, Vikrant, et al.
Publicado: (2022)

COVID19 Drug Repository: text-mining the literature in search of putative COVID19 therapeutics
por: Tworowski, Dmitry, et al.
Publicado: (2020)

ChiPPI: a novel method for mapping chimeric protein–protein interactions uncovers selection principles of protein fusion events in cancer
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2017)

The Landscape of Novel Expressed Chimeric RNAs in Rheumatoid Arthritis
por: Detroja, Rajesh, et al.
Publicado: (2022)

The Landscape of Expressed Chimeric Transcripts in the Blood of Severe COVID-19 Infected Patients
por: Mukherjee, Sunanda Biswas, et al.
Publicado: (2023)

SALMONELLABASE - An online database of druggable targets of Salmonella species
por: Pushpa, Ophilia Benedict, et al.
Publicado: (2012)

EvoProDom: evolutionary modeling of protein families by assessing translocations of protein domains
por: Carmi, Gon, et al.
Publicado: (2021)

Dr. PIAS: an integrative system for assessing the druggability of protein-protein interactions
por: Sugaya, Nobuyoshi, et al.
Publicado: (2011)

Novel domain combinations in proteins encoded by chimeric transcripts
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2012)

ProtFus: A Comprehensive Method Characterizing Protein-Protein Interactions of Fusion Proteins
por: Tagore, Somnath, et al.
Publicado: (2019)

Pharos: Collating protein information to shed light on the druggable genome
por: Nguyen, Dac-Trung, et al.
Publicado: (2017)

The chromatin remodeler Chd1 regulates cohesin in budding yeast and humans
por: Boginya, Alexandra, et al.
Publicado: (2019)

Emerging Role of Chimeric RNAs in Cell Plasticity and Adaptive Evolution of Cancer Cells
por: Mukherjee, Sumit, et al.
Publicado: (2021)

Immunoinformatics and Structural Analysis for Identification of Immunodominant Epitopes in SARS-CoV-2 as Potential Vaccine Targets
por: Mukherjee, Sumit, et al.
Publicado: (2020)

Seasonal UV exposure and vitamin D: association with the dynamics of COVID‐19 transmission in Europe
por: Mukherjee, Sunanda Biswas, et al.
Publicado: (2021)

Dr. PIAS 2.0: an update of a database of predicted druggable protein–protein interactions
por: Sugaya, Nobuyoshi, et al.
Publicado: (2012)

RATEmiRs: the rat atlas of tissue-specific and enriched miRNAs database
por: Bushel, Pierre R., et al.
Publicado: (2018)

microbioTA: an atlas of the microbiome in multiple disease tissues of Homo sapiens and Mus musculus
por: Wang, Ping, et al.
Publicado: (2022)

HgsDb: Haplogroups Database to understand migration and molecular risk assessment
por: Arora, Devender, et al.
Publicado: (2015)

ChimerDB 4.0: an updated and expanded database of fusion genes
por: Jang, Ye Eun, et al.
Publicado: (2020)

The Association of Previous Vaccination with Live-Attenuated Varicella Zoster Vaccine and COVID-19 Positivity: An Israeli Population-Based Study
por: Merzon, Eugene, et al.
Publicado: (2022)

OrchidBase 5.0: updates of the orchid genome knowledgebase
por: Chen, You-Yi, et al.
Publicado: (2022)

Incipient Sympatric Speciation and Evolution of Soil Bacteria Revealed by Metagenomic and Structured Non-Coding RNAs Analysis
por: Mukherjee, Sumit, et al.
Publicado: (2022)

ChimerDB 3.0: an enhanced database for fusion genes from cancer transcriptome and literature data mining
por: Lee, Myunggyo, et al.
Publicado: (2017)

Chimeras taking shape: Potential functions of proteins encoded by chimeric RNA transcripts
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2012)

Altered Expression and Localization of Tumor Suppressive E3 Ubiquitin Ligase SMURF2 in Human Prostate and Breast Cancer
por: Emanuelli, Andrea, et al.
Publicado: (2019)

ClusterCAD 2.0: an updated computational platform for chimeric type I polyketide synthase and nonribosomal peptide synthetase design
por: Tao, Xavier B, et al.
Publicado: (2022)

Clinical and Molecular Characterization of a Rare Case of BNT162b2 mRNA COVID-19 Vaccine-Associated Myositis
por: Magen, Eli, et al.
Publicado: (2022)

tRNA methylation resolves codon usage bias at the limit of cell viability
por: Masuda, Isao, et al.
Publicado: (2022)

HMDB 5.0: the Human Metabolome Database for 2022
por: Wishart, David S, et al.
Publicado: (2021)

Enhanced annotations and features for comparing thousands of Pseudomonas genomes in the Pseudomonas genome database
por: Winsor, Geoffrey L., et al.
Publicado: (2016)

PLAZA 5.0: extending the scope and power of comparative and functional genomics in plants
por: Van Bel, Michiel, et al.
Publicado: (2021)

Refining intra-protein contact prediction by graph analysis
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2007)

One-Block CYRCA: an automated procedure for identifying multiple-block alignments from single block queries
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_oj3u0dnhjv2dpbhp3igap65p91