A PARP1–BRG1–SIRT1 axis promotes HR repair by reducing nucleosome density at DNA damage sites

Creating access to DNA double-strand break (DSB) sites in the chromatin context is an essential step during the repair process, but much remains to be determined about its regulatory mechanisms. Here, using a novel reporter cassette for simultaneous detection of homologous recombination (HR) and non...

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Detalles Bibliográficos
Autores principales: Chen, Yu, Zhang, Haiping, Xu, Zhu, Tang, Huanyin, Geng, Anke, Cai, Bailian, Su, Tao, Shi, Jiejun, Jiang, Cizhong, Tian, Xiao, Seluanov, Andrei, Huang, Jun, Wan, Xiaoping, Jiang, Ying, Gorbunova, Vera, Mao, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145522/
https://www.ncbi.nlm.nih.gov/pubmed/31291457
http://dx.doi.org/10.1093/nar/gkz592

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