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The mRNA repressor TRIM71 cooperates with Nonsense-Mediated Decay factors to destabilize the mRNA of CDKN1A/p21
Nonsense-mediated decay (NMD) plays a fundamental role in the degradation of premature termination codon (PTC)-containing transcripts, but also regulates the expression of functional transcripts lacking PTCs, although such ‘non-canonical’ functions remain ill-defined and require the identification o...
Autores principales: | Torres-Fernández, Lucia A, Jux, Bettina, Bille, Maximilian, Port, Yasmine, Schneider, Karin, Geyer, Matthias, Mayer, Günter, Kolanus, Waldemar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145526/ https://www.ncbi.nlm.nih.gov/pubmed/31732746 http://dx.doi.org/10.1093/nar/gkz1057 |
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