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Structure–fluorescence activation relationships of a large Stokes shift fluorogenic RNA aptamer

The Chili RNA aptamer is a 52 nt long fluorogen-activating RNA aptamer (FLAP) that confers fluorescence to structurally diverse derivatives of fluorescent protein chromophores. A key feature of Chili is the formation of highly stable complexes with different ligands, which exhibit bright, highly Sto...

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Detalles Bibliográficos
Autores principales: Steinmetzger, Christian, Bessi, Irene, Lenz, Ann-Kathrin, Höbartner, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145527/
https://www.ncbi.nlm.nih.gov/pubmed/31740962
http://dx.doi.org/10.1093/nar/gkz1084