Human RAD51 paralogue RAD51C fosters repair of alkylated DNA by interacting with the ALKBH3 demethylase

The integrity of our DNA is challenged daily by a variety of chemicals that cause DNA base alkylation. DNA alkylation repair is an essential cellular defence mechanism to prevent the cytotoxicity or mutagenesis from DNA alkylating chemicals. Human oxidative demethylase ALKBH3 is a central component...

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Detalles Bibliográficos
Autores principales: Mohan, Monisha, Akula, Deepa, Dhillon, Arun, Goyal, Arun, Anindya, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145530/
https://www.ncbi.nlm.nih.gov/pubmed/31642493
http://dx.doi.org/10.1093/nar/gkz938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145530/
https://www.ncbi.nlm.nih.gov/pubmed/31642493
http://dx.doi.org/10.1093/nar/gkz938

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