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WormBase: a modern Model Organism Information Resource

WormBase (https://wormbase.org/) is a mature Model Organism Information Resource supporting researchers using the nematode Caenorhabditis elegans as a model system for studies across a broad range of basic biological processes. Toward this mission, WormBase efforts are arranged in three primary face...

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Detalles Bibliográficos
Autores principales: Harris, Todd W, Arnaboldi, Valerio, Cain, Scott, Chan, Juancarlos, Chen, Wen J, Cho, Jaehyoung, Davis, Paul, Gao, Sibyl, Grove, Christian A, Kishore, Ranjana, Lee, Raymond Y N, Muller, Hans-Michael, Nakamura, Cecilia, Nuin, Paulo, Paulini, Michael, Raciti, Daniela, Rodgers, Faye H, Russell, Matthew, Schindelman, Gary, Auken, Kimberly V, Wang, Qinghua, Williams, Gary, Wright, Adam J, Yook, Karen, Howe, Kevin L, Schedl, Tim, Stein, Lincoln, Sternberg, Paul W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145598/
https://www.ncbi.nlm.nih.gov/pubmed/31642470
http://dx.doi.org/10.1093/nar/gkz920
Descripción
Sumario:WormBase (https://wormbase.org/) is a mature Model Organism Information Resource supporting researchers using the nematode Caenorhabditis elegans as a model system for studies across a broad range of basic biological processes. Toward this mission, WormBase efforts are arranged in three primary facets: curation, user interface and architecture. In this update, we describe progress in each of these three areas. In particular, we discuss the status of literature curation and recently added data, detail new features of the web interface and options for users wishing to conduct data mining workflows, and discuss our efforts to build a robust and scalable architecture by leveraging commercial cloud offerings. We conclude with a description of WormBase's role as a founding member of the nascent Alliance of Genome Resources.