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WormBase: a modern Model Organism Information Resource
WormBase (https://wormbase.org/) is a mature Model Organism Information Resource supporting researchers using the nematode Caenorhabditis elegans as a model system for studies across a broad range of basic biological processes. Toward this mission, WormBase efforts are arranged in three primary face...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145598/ https://www.ncbi.nlm.nih.gov/pubmed/31642470 http://dx.doi.org/10.1093/nar/gkz920 |
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author | Harris, Todd W Arnaboldi, Valerio Cain, Scott Chan, Juancarlos Chen, Wen J Cho, Jaehyoung Davis, Paul Gao, Sibyl Grove, Christian A Kishore, Ranjana Lee, Raymond Y N Muller, Hans-Michael Nakamura, Cecilia Nuin, Paulo Paulini, Michael Raciti, Daniela Rodgers, Faye H Russell, Matthew Schindelman, Gary Auken, Kimberly V Wang, Qinghua Williams, Gary Wright, Adam J Yook, Karen Howe, Kevin L Schedl, Tim Stein, Lincoln Sternberg, Paul W |
author_facet | Harris, Todd W Arnaboldi, Valerio Cain, Scott Chan, Juancarlos Chen, Wen J Cho, Jaehyoung Davis, Paul Gao, Sibyl Grove, Christian A Kishore, Ranjana Lee, Raymond Y N Muller, Hans-Michael Nakamura, Cecilia Nuin, Paulo Paulini, Michael Raciti, Daniela Rodgers, Faye H Russell, Matthew Schindelman, Gary Auken, Kimberly V Wang, Qinghua Williams, Gary Wright, Adam J Yook, Karen Howe, Kevin L Schedl, Tim Stein, Lincoln Sternberg, Paul W |
author_sort | Harris, Todd W |
collection | PubMed |
description | WormBase (https://wormbase.org/) is a mature Model Organism Information Resource supporting researchers using the nematode Caenorhabditis elegans as a model system for studies across a broad range of basic biological processes. Toward this mission, WormBase efforts are arranged in three primary facets: curation, user interface and architecture. In this update, we describe progress in each of these three areas. In particular, we discuss the status of literature curation and recently added data, detail new features of the web interface and options for users wishing to conduct data mining workflows, and discuss our efforts to build a robust and scalable architecture by leveraging commercial cloud offerings. We conclude with a description of WormBase's role as a founding member of the nascent Alliance of Genome Resources. |
format | Online Article Text |
id | pubmed-7145598 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-71455982020-04-13 WormBase: a modern Model Organism Information Resource Harris, Todd W Arnaboldi, Valerio Cain, Scott Chan, Juancarlos Chen, Wen J Cho, Jaehyoung Davis, Paul Gao, Sibyl Grove, Christian A Kishore, Ranjana Lee, Raymond Y N Muller, Hans-Michael Nakamura, Cecilia Nuin, Paulo Paulini, Michael Raciti, Daniela Rodgers, Faye H Russell, Matthew Schindelman, Gary Auken, Kimberly V Wang, Qinghua Williams, Gary Wright, Adam J Yook, Karen Howe, Kevin L Schedl, Tim Stein, Lincoln Sternberg, Paul W Nucleic Acids Res Database Issue WormBase (https://wormbase.org/) is a mature Model Organism Information Resource supporting researchers using the nematode Caenorhabditis elegans as a model system for studies across a broad range of basic biological processes. Toward this mission, WormBase efforts are arranged in three primary facets: curation, user interface and architecture. In this update, we describe progress in each of these three areas. In particular, we discuss the status of literature curation and recently added data, detail new features of the web interface and options for users wishing to conduct data mining workflows, and discuss our efforts to build a robust and scalable architecture by leveraging commercial cloud offerings. We conclude with a description of WormBase's role as a founding member of the nascent Alliance of Genome Resources. Oxford University Press 2020-01-08 2019-10-23 /pmc/articles/PMC7145598/ /pubmed/31642470 http://dx.doi.org/10.1093/nar/gkz920 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Database Issue Harris, Todd W Arnaboldi, Valerio Cain, Scott Chan, Juancarlos Chen, Wen J Cho, Jaehyoung Davis, Paul Gao, Sibyl Grove, Christian A Kishore, Ranjana Lee, Raymond Y N Muller, Hans-Michael Nakamura, Cecilia Nuin, Paulo Paulini, Michael Raciti, Daniela Rodgers, Faye H Russell, Matthew Schindelman, Gary Auken, Kimberly V Wang, Qinghua Williams, Gary Wright, Adam J Yook, Karen Howe, Kevin L Schedl, Tim Stein, Lincoln Sternberg, Paul W WormBase: a modern Model Organism Information Resource |
title | WormBase: a modern Model Organism Information Resource |
title_full | WormBase: a modern Model Organism Information Resource |
title_fullStr | WormBase: a modern Model Organism Information Resource |
title_full_unstemmed | WormBase: a modern Model Organism Information Resource |
title_short | WormBase: a modern Model Organism Information Resource |
title_sort | wormbase: a modern model organism information resource |
topic | Database Issue |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145598/ https://www.ncbi.nlm.nih.gov/pubmed/31642470 http://dx.doi.org/10.1093/nar/gkz920 |
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